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A liver transplant is a surgical procedure that replaces a liver that is diseased or no longer functions properly with a liver from a deceased donor or a portion of a healthy liver from a living donor. The living donor can be:
Someone who is emotionally related to the recipient such as a good friend, a significant other, or a spouse.
A family member of the recipient, such as a parent, adult child, brother, or sister.
Other biologically related relatives, such as an aunt, uncle, or cousin.
A person who has heard about the transplant candidate’s need.
Altruistic donation or non-directed living-donor. This means that the donor does not know or name the recipient of the donated liver. The match is based on blood type compatibility and medical need. The donor may choose not to know the recipient or may meet if both agree.
When the living donor is a family member, it is called a living related donor liver transplant.
Living related donor liver transplant is usually used as an alternative to waiting for a deceased donor liver or an altruistic donation to become available. A liver transplant from a living donor is possible because the human liver can regenerate and return to its normal size, capacity, and volume within a couple of months after surgical removal of part of the organ. The transplanted liver portion in the recipient will grow and restore normal liver function as well.
Not everyone can be a living related donor. The donor has to be healthy and able to safely undergo major surgery. In addition, the donor’s blood type, age, and organ size are critical considerations in determining whether the recipient and the donor are a match. Extensive health and psychological evaluation are required to make sure that the donor and the recipient are a match, as well as to assess the donor’s mental and physical health.
A liver transplant surgery from a living donor is usually scheduled in advance.
The surgeons will first operate on the donor. The surgery is done under general anesthesia, a portion of the donor's liver is removed through an incision in the abdomen. Both the left and right lobe of the liver can be used for donation. The specific part of the liver donated depends on the donor liver’s size and the recipient’s needs. Around 40% to 70% of the donor’s liver is removed for transplantation.
Once the donor's liver is ready, the surgeons will perform the liver transplant on you (the recipient). During this surgery, an anesthesiologist will give you a general anesthetic. After you are anesthetized, the surgeons will create an incision under the ribs on both sides of your belly and separate the diseased liver from the nearby organs and structures to carefully remove it. Then, the donated liver portion will be placed in your body by connecting the bile ducts and blood vessels to the new liver. The final step is closing the incision with stitches or surgical staples.
After a living related donor liver transplant, you should expect to spend 5 to 10 days in the hospital. Expect to stay in United Kingdom for at least a month after you are discharged from the hospital as you need to attend follow-up checkups. Your liver transplant team will design a checkup schedule for you. Laboratory blood tests are typically obtained twice a week after transplantation and will be reduced gradually. You must attend all of the follow-up checkups and blood tests because your doctor needs to check your condition.
The recovery period depends on the severity of your condition before your liver transplant surgery. In general, the full recovery time until you feel fully healed after your liver transplant surgery can take around six months or more. However, you should be able to return to some of your normal activities, including work (office job) within 2 to 4 months following your surgery. Simple activities of daily living may be resumed within a few weeks.
You will take medication for the rest of your life – the medications are called immunosuppressant (anti-rejection medicines), which works by keeping your immune system from attacking your new liver. They are used to help the transplanted liver survive in your body.
You will take other medications – you may need other types of medications to help reduce the risk of other complications.
Avoid crowds or anyone who has an infection – anti-rejection medicines affect your immune system, increasing your risk of infections. Therefore, you need to avoid contact with anyone who has an infection or crowds for the first few months.
Eat a well-balanced diet –to help you recover and keep your new liver healthy. A dietitian from your transplant team will discuss your nutrition and diet needs. In general, your diet should be low in fat, salt, cholesterol, and sugar. You also need to avoid alcohol.
Exercise regularly – walk as much as you can soon after your transplant. Then, start to incorporate more physical activity into your daily life. Make sure to check in with your transplant team before starting an exercise routine.
The success rate of the liver transplant depends on your specific situation. In general, around 75% of people who have a liver transplant live for at least five years. People who receive a liver from a living related donor usually have longer survival rates than those who receive a deceased donor liver. Also, people who have a living related donor liver transplant seem to experience fewer medical problems.
The risks and side effects associated with liver transplant include rejection of the donated liver, bleeding, bile duct complications, failure of donated liver, infection, mental confusion, seizures, and recurrence of liver disease in the transplanted liver.
There are currently no alternatives to a liver transplant. However, the alternative to living related donor liver transplant is to wait for a deceased donor liver or an altruistic donation to become available. Make sure to discuss with your doctor the best option for your case.
Before a living related liver transplant, you may have acute or chronic liver failure, which may be caused by a variety of conditions, or you may have certain cancers that originate in the liver. After the procedure, these conditions may be cured. Your survival rates will be increased significantly after the procedure.
Whilst the information presented here has been accurately sourced and verified by a medical professional for its accuracy, it is still advised to consult with your doctor before pursuing a medical treatment at one of the listed medical providers
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The United Kingdom is a constitutional monarchy comprising much of the British Isles. This Union is more than 300 years old and comprises four constituent countries: England, Scotland, Wales, and Northern Ireland. It occupies all of the island of Great Britain, the north-eastern portion of the island of Ireland, and most of the remaining British Isles. The UK is an island nation but shares an open land border with Ireland. The UK has a population of 65 million people, the capital and largest city is London.
The United Kingdom welcomes an ever-increasing number of medical tourists each year, many of which travel for Liver Transplant (Living Related Donor) procedures. The government provides all British citizens free or low-cost care under the NHS, also known as the National Health System, leaving a small private sector for routine operations, which caters to people that do not want to wait in line for elective procedures or are not citizens or residents of the Islands.
Made up of Great Britain and Northern Ireland, the United Kingdom is filled with vibrant cities and tranquil countryside.
The United Kingdom enjoys a temperate climate and has plenty of rain all year round. Tourists can visit any time of year as it does not experience extreme weather. There is a great variety of changeable weather, but the overall weather and seasons are generally the same throughout this sovereign country.
There are plenty of airports in the United Kingdom, but the busiest and the largest airport is the London Heathrow Airport. It is the second busiest airport in the world after Dubai Airport. The airport has international connections with almost every country around the globe, including countries in the Middle East, Asia, Africa, and North America. It also serves domestic flights which provide an easy way to travel around the United Kingdom. There are budget airlines that offer a more affordable option for those who want to get around by plane.
The United Kingdom is very well connected by plane, train, and bus. The train is the most popular mode of transport and one of the most comfortable. Tickets can be booked online and it can be expensive, but most trains are equipped with air conditioning and sometimes Wi-Fi. There are two classes of train, the Standard Class and the First Class. Big cities and towns are usually connected by a regular bus service. The cost can be cheap, but the further you travel away from a city, the more expensive the cost. It is best to invest in an Oyster Card if you wish to travel by bus.
Taxis are available in most cities. There are two types of taxis; the metered taxis (painted in black) and private hire taxis (known as minicabs). The taxis should have a taxi-license displayed on the dashboard. The metered taxis can be hailed directly from the streets, while the minicabs have to be ordered via telephone. The minicabs are usually more affordable than the metered taxis because they operate on fixed prices and sometimes are even open to negotiation.
Citizens of the European Union can enter the United Kingdom without a visa. Additionally, British Nationals who are not European Union citizens and nationals of 56 countries can enter and stay for up to 180 days (90 days if they enter from the Republic of Ireland). Citizens of Kuwait, Oman, Qatar, and the UAE can obtain an online electronic visa waiver (EVW). Other nationals not listed in the visa-exempt for stays in the UK (including China and Russia) need to apply and obtain a visa before entering the country.