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A liver transplant is a surgical procedure that replaces a liver that is diseased or no longer functions properly with a liver from a deceased donor or a portion of a healthy liver from a living donor. The living donor can be:
Someone who is emotionally related to the recipient such as a good friend, a significant other, or a spouse.
A family member of the recipient, such as a parent, adult child, brother, or sister.
Other biologically related relatives, such as an aunt, uncle, or cousin.
A person who has heard about the transplant candidate’s need.
Altruistic donation or non-directed living-donor. This means that the donor does not know or name the recipient of the donated liver. The match is based on blood type compatibility and medical need. The donor may choose not to know the recipient or may meet if both agree.
When the living donor is a family member, it is called a living related donor liver transplant.
Living related donor liver transplant is usually used as an alternative to waiting for a deceased donor liver or an altruistic donation to become available. A liver transplant from a living donor is possible because the human liver can regenerate and return to its normal size, capacity, and volume within a couple of months after surgical removal of part of the organ. The transplanted liver portion in the recipient will grow and restore normal liver function as well.
Not everyone can be a living related donor. The donor has to be healthy and able to safely undergo major surgery. In addition, the donor’s blood type, age, and organ size are critical considerations in determining whether the recipient and the donor are a match. Extensive health and psychological evaluation are required to make sure that the donor and the recipient are a match, as well as to assess the donor’s mental and physical health.
A liver transplant surgery from a living donor is usually scheduled in advance.
The surgeons will first operate on the donor. The surgery is done under general anesthesia, a portion of the donor's liver is removed through an incision in the abdomen. Both the left and right lobe of the liver can be used for donation. The specific part of the liver donated depends on the donor liver’s size and the recipient’s needs. Around 40% to 70% of the donor’s liver is removed for transplantation.
Once the donor's liver is ready, the surgeons will perform the liver transplant on you (the recipient). During this surgery, an anesthesiologist will give you a general anesthetic. After you are anesthetized, the surgeons will create an incision under the ribs on both sides of your belly and separate the diseased liver from the nearby organs and structures to carefully remove it. Then, the donated liver portion will be placed in your body by connecting the bile ducts and blood vessels to the new liver. The final step is closing the incision with stitches or surgical staples.
After a living related donor liver transplant, you should expect to spend 5 to 10 days in the hospital. Expect to stay in Israel for at least a month after you are discharged from the hospital as you need to attend follow-up checkups. Your liver transplant team will design a checkup schedule for you. Laboratory blood tests are typically obtained twice a week after transplantation and will be reduced gradually. You must attend all of the follow-up checkups and blood tests because your doctor needs to check your condition.
The recovery period depends on the severity of your condition before your liver transplant surgery. In general, the full recovery time until you feel fully healed after your liver transplant surgery can take around six months or more. However, you should be able to return to some of your normal activities, including work (office job) within 2 to 4 months following your surgery. Simple activities of daily living may be resumed within a few weeks.
You will take medication for the rest of your life – the medications are called immunosuppressant (anti-rejection medicines), which works by keeping your immune system from attacking your new liver. They are used to help the transplanted liver survive in your body.
You will take other medications – you may need other types of medications to help reduce the risk of other complications.
Avoid crowds or anyone who has an infection – anti-rejection medicines affect your immune system, increasing your risk of infections. Therefore, you need to avoid contact with anyone who has an infection or crowds for the first few months.
Eat a well-balanced diet –to help you recover and keep your new liver healthy. A dietitian from your transplant team will discuss your nutrition and diet needs. In general, your diet should be low in fat, salt, cholesterol, and sugar. You also need to avoid alcohol.
Exercise regularly – walk as much as you can soon after your transplant. Then, start to incorporate more physical activity into your daily life. Make sure to check in with your transplant team before starting an exercise routine.
The success rate of the liver transplant depends on your specific situation. In general, around 75% of people who have a liver transplant live for at least five years. People who receive a liver from a living related donor usually have longer survival rates than those who receive a deceased donor liver. Also, people who have a living related donor liver transplant seem to experience fewer medical problems.
The risks and side effects associated with liver transplant include rejection of the donated liver, bleeding, bile duct complications, failure of donated liver, infection, mental confusion, seizures, and recurrence of liver disease in the transplanted liver.
There are currently no alternatives to a liver transplant. However, the alternative to living related donor liver transplant is to wait for a deceased donor liver or an altruistic donation to become available. Make sure to discuss with your doctor the best option for your case.
Before a living related liver transplant, you may have acute or chronic liver failure, which may be caused by a variety of conditions, or you may have certain cancers that originate in the liver. After the procedure, these conditions may be cured. Your survival rates will be increased significantly after the procedure.
Whilst the information presented here has been accurately sourced and verified by a medical professional for its accuracy, it is still advised to consult with your doctor before pursuing a medical treatment at one of the listed medical providers
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Israel celebrated 70 years of independence in 2018 - in what is a truly ancient land. The world’s only Jewish and democratic state is home to sites sacred to Judaism, Christianity, and Islam. While these holy places are truly unique attractions, there is more to Israel than religious heritage and complex politics. Jerusalem is the official capital and holy city to three world religions, previously mentioned, while Tel Aviv brims with beaches and bustles with urban vitality. Then there’s the Dead Sea and Masada, the stark, stunning Negev, and fertile Galilee. The number of museums and cultural institutions per relative area is larger in Israel than anywhere in the world.
Home to more than 30 JCI accredited facilities, medical tourists visit Israel for a variety of procedures, but particularly dental and tertiary care. Liver Transplant (Living Related Donor) procedures are also a popular choice.
Israel is an alluring destination for those who want to appreciate its astonishing religious sites, stunning natural beauty, and remarkable historic relics.
Israel is a year-round destination but the temperatures in the city vary widely. The coastal areas such as Tel Aviv and Haifa experiences a typical Mediterranean climate where the winters are rainy and the summers are hot. The area around Northern Negev has a semi-arid climate with hot summers and cool winters. The Southern Negev has a desert climate with extremely hot summers and mild winters. On the other hand, mountainous regions have pleasant summer and cold winters with a little snowfall.
Generally, the winter months from November to March are the coldest months in the country. When mountainous areas such as Jerusalem receives snowfall, the coastal areas experience heavy rainfall. Summer starts in June and ends in August and it is the hottest season in every part of the country, especially in the desert area where the heat can be overbearing. The seasons of spring and autumn have the best weather, with pleasant temperatures and fewer rainy days.
Ben Gurion Airport is the main gateway to Israel and it is the busiest airport in the country located 20 kilometers southeast of Tel Aviv and 45 kilometers northwest of Jerusalem. The airport is ranked among the five best airports in the Middle East. It serves both domestic and international flights to and from numerous major cities around the world. There is two main passenger terminal at this airport. Terminal 1 serves domestic flights and international budget airlines such as EasyJet and Vueling, while Terminal 3 serves international flights.
Since the distance between one city to another is relatively short, getting around Israel is easy. The quickest and most convenient way is by domestic flights. The tickets are not very expensive and deals are often available online. Sometimes a one-way ticket can cost as little as 89 NIS (25 USD). Buses are also convenient but can be slow during traffic jams. Buses connecting Jerusalem, Tel Aviv, and Haifa depart very frequently. A one-way ticket from Tel Aviv to Jerusalem is around 25 NIS (7 USD). Israel’s main bus company is the Egged Bus Company. Trains are also available and very comfortable. They are a lot faster than the bus but the cost can be higher.
Taxis are widely available and can be hailed directly from the streets. Although most taxis are metered, you can agree on a fixed rate and be aware that some drivers are known to overcharge tourists, so you should insist on using the meter and make sure that it is reset to the base fare after you get in. The base fare is normally around 12.30 NIS (3.5 USD). There is also a shared taxi van known as Sherut. It is a good option to travel between Tel Aviv and Jerusalem or Tel Aviv and Haifa.
All visitors must hold a passport valid for at least six months after the date of departure from Israel. Citizens of 99 countries including the European Union, Canada, Singapore, Russia, and the United States do not require a visa to enter the country for up to 3 months. Nationals not listed on the visa exemption agreement need to obtain a visa and should contact their nearest embassy of Israel. Citizens of 25 countries require a confirmation from the Israeli government before a tourist visa is issued.